Even if I don’t know what I’m making for dinner, I can count on having a few pounds of ground beef in my freezer. On days like that, I pull it out, let it thaw, and make one of many favorite ground beef recipes. And often, it’s this simple and so-good classic meatloaf recipe, which is one of the first things my son lists when I ask him which dinners he wants me to make during the week.

Recipe Highlights
10 minutes of prep: It takes me only about 10 minutes to combine all of the ingredients for this best meatloaf recipe and get it packed into a loaf pan. I often do this in the morning and stick it in the fridge until it’s time to bake the meatloaf for dinner.
Use what’s on hand: This recipe can be made with different ground meats (or a mix of them), different types of onions and veggies, different seasoning, different crackers or breadcrumbs, and different sauces. In that way, I think it’s a great recipe for using up random things in my pantry and fridge.
High protein comfort food: Not only is this recipe a classic comfort food that is loved by many, but it’s also a great way to help meet protein goals, providing 33 grams of protein per serving.

Ingredient Notes And Substitutions
I’m all about easy dinner recipes that require simple real-food ingredients that are easy to find. This easy meatloaf recipe is straightforward, with just the right amount of everyday spices and add-ins to make it tender, flavorful, and moist.
- Ground beef – I use two pounds of quality lean ground beef sourced from a local locker in my hometown. But I’ve also made this meatloaf with a mix of ground beef and ground venison (1 lb each), and ground turkey and ground pork works, too.
- Bread crumbs – I typically use homemade breadcrumbs that I make from leftover sourdough bread once it has gotten a little too hard. But panko breadcrumbs, crushed crackers, or quick oats also work as a substitute. I don’t recommend old-fashioned oats, since they won’t break down enough. See below for my gluten-free recommendations.
- Coconut aminos – This condiment is a lot like soy sauce, but it’s made from the sap of young coconut trees. It’s naturally gluten free and lower in sodium than soy sauce. However, if soy sauce is all that’s on hand, use that instead of the coconut aminos and then just omit the salt in this recipe.
- Dijon mustard – I like the tang and pop of flavor that I get from the acidity of Dijon mustard, though any mustard variety will work, such as yellow mustard or whole grain mustard, or substitute 1 tablespoon of vinegar in place of the 2 tablespoons mustard.
- Ketchup – I tend to top my meatloaf with ⅓ cup ketchup and find that it’s perfect for creating that sweet glaze on top, even without adding any brown sugar. Barbecue sauce or marinara sauce are fine substitutes.
Find the ingredient list with exact measurements in the recipe card below.


How To Make This Simple Weeknight Dinner
After making this homemade meatloaf recipe so many times, I have a few tips for success:
- Pick the right binder: Meatloaf needs a binding agent to help it hold together when sliced, a lot how a hamburger holds together. In my recipe, eggs and breadcrumbs act as the binders. The first time I made this meatloaf, I soaked the breadcrumbs in ¼ cup milk in a small bowl, but that extra step didn’t make much difference in the cooked meatloaf, so now I skip it.
- Don’t over handle it: The more the meat mixture is handled, combined, and shaped, the tougher and more dense the meatloaf will become. I prefer to mix the ingredients in a large bowl with my hands, ensuring that they get intertwined and mixed but not completely patted down. I loosely shape the loaf before putting it in the pan so I can avoid having to press it too firmly into the pan.
- Include flavor boosters: There are many mix-ins that can give meatloaf a ton of flavor and a new recipe spin. I tend to make meatloaf with Dijon mustard, coconut aminos (or soy sauce), garlic powder or minced garlic, finely chopped onion or onion powder, plus simple salt and pepper. Other good mix-ins include Worcestershire sauce, finely chopped bell pepper, Italian seasoning or other aromatics.
- Add a topper: Most meatloaf recipes include a sauce on top, and most often it’s ketchup. I like ketchup, too, since it provides a nice sweet and savory saucy balance to the meat. I also think that barbecue sauce is a good substitute, and I’ll use marinara sauce in a pinch.
- Bake to 160℉: I prefer to use temperature to indicate when the meatloaf is done. I use a meat thermometer to check when the meatloaf just reaches 160℉ (which takes about an hour), then I pull it out of the oven and let the meatloaf sit for 5 minutes before draining off excess grease and slicing it.
For serving size and the complete directions and ingredient amounts, scroll down to the recipe card below. All of our recipes include the nutrition analysis, listing calories (kcals), protein, carbohydrates/carb, fiber, sugar, sodium, cholesterol, and more per serving.

Make It Gluten Free
It’s easy to make this meatloaf recipe gluten free with one simple swap. Instead of regular breadcrumbs, use gluten-free breadcrumbs, gluten-free crushed crackers, or certified gluten-free quick oats.
Comforting Side Dish Pairings
I like to serve this classic meatloaf as the main dish with other comfort food sides, like these creamy mashed potatoes plus a veggie side of simple sautéed green beans. To me, that is just a cozy nourishing meal at its best.

Prep Ahead For Busy Weeks
This is a great recipe for someone starting to do more meal prep, since it doesn’t take long to mix all the meatloaf ingredients together. I’ll often do that, up to the point of putting the raw meatloaf in the loaf pan, in the morning and then just store the unbaked meatloaf in the fridge until it’s ready to bake later. This also can be done up to 2 days ahead of baking it, then I just pull it out of the fridge while I preheat oven and make some sides. It still reaches 160℉ at about 1 hour of baking.
Store And Enjoy Leftovers Later
I let any remaining meatloaf cool to room temperature, then I store it in an airtight container in the fridge for up to 4 days. To reheat, I reheat a portion in my toaster oven (or reheating in a skillet on the stovetop or in the microwave also works).
Personally, I don’t think someone has lived until they’ve tried a leftover meatloaf sandwich. Here’s how I make one at the Slama homestead: Heat a leftover meatloaf slice in a skillet on the stovetop over medium heat until it is warmed through, about 2 to 3 minutes per side. I’m not trying to cook the meatloaf further, just heating it up to get those edges slightly caramelized and crispy. Then I place the slice between two pieces of bread or on a bun and add a spoonful of coleslaw, some pickled red onions, or a few dill pickle chips. It’s so good!

Frequently Asked Questions
There are pros and cons to both methods. I prefer using a loaf pan because it’s an easier way to manage the soft uncooked meatloaf mixture, and I also think making it in a baking dish results in a more tender and moist meatloaf.
Advocates of the sheet pan method, however, say that cooking meatloaf on a sheet pan creates more even cooking throughout and a firmer texture with a crispier exterior. The fat also leaks out of the meatloaf while cooking (so be sure to use a rimmed baking sheet), which cuts down a bit on the saturated fat and trans fat that is naturally in ground beef.
Yes, the meatloaf mixture can be combined ahead of time, shaped into a loaf, and then frozen in a freezer-safe silicone pan or wrapped in plastic wrap and aluminum foil and then placed in a freezer-safe bag until ready to bake. Then, thaw the frozen loaf in the refrigerator overnight before baking it. Bake until the internal temperature at the center of the meatloaf reaches 160℉.
Want to save this recipe?
Enter your email below & we’ll send it straight to your inbox. Plus you’ll get great new recipes from us every week!
Meatloaf Recipe
This classic meatloaf recipe is always a comforting, nourishing, high-protein dinner that comes together quickly. Prep it whenever you have 10 minutes to spare in the day, then store it in the fridge until ready to bake for dinner.
Ingredients
- Cooking spray
- 2 lbs lean ground beef*
- ½ cup bread crumbs*
- 1 small yellow or white onion, diced (~½ cup)
- 2 large eggs
- 2 tablespoons Dijon mustard
- 1 tablespoon coconut aminos*
- 2 teaspoon garlic powder
- 1 teaspoon fine salt
- ¼ – ½ teaspoon ground black pepper
- ⅓ cup unsweetened ketchup*
- Optional garnish: finely chopped fresh parsley
Instructions
- Preheat the oven to 375℉ and lightly mist a 9×5-inch loaf pan with cooking spray; set aside.
- In a medium bowl, combine the ground beef, bread crumbs, diced onion, eggs, mustard, coconut aminos, garlic powder, salt, and pepper until well combined. Mix by hand or with a wooden spoon just until the ingredients are incorporated (NOTE: Avoid overmixing the meatloaf mixture since that could make the meatloaf too dense.)
- Transfer the meatloaf mixture to the prepared loaf pan and gently press into an even layer.
- Spread the ketchup over the top of the meatloaf mixture in an even layer.
- Bake until an instant read thermometer inserted into the center of the meatloaf reads 160℉, about 1 hour.
- Remove the meatloaf from the oven and carefully pour any excess fat from the pan to discard.
- Let the meatloaf rest for 5 minutes before slicing and serving.
- Store leftovers in an airtight container in the refrigerator for up to 4 days.
Last Step! Please leave a review and rating letting us know how you liked this recipe! This helps our business thrive so we can continue providing free recipes and high-quality content for you.
Notes
* Substitutions:
– May use ground turkey, ground venison, or ground pork (or a mix) in place of the ground beef.
– May substitute crushed crackers or quick oats in place of the breadcrumbs.
– May use 1 tablespoon soy sauce or tamari in place of the 1 tablespoon coconut aminos, and then also omit the salt.
– May substitute barbecue sauce or marinara sauce in place of the ketchup.
For gluten free, use gluten-free breadcrumbs, crushed gluten-free crackers, or certified gluten-free quick oats.
Nutrition Information
- Serving Size: 1/6 of the meatloaf
- Calories: 342
- Fat: 17 g
- (Sat Fat: 6 g)
- Sodium: 832 mg
- Carbohydrate: 11 g
- (Fiber: 1 g
- Sugar: 3 g)
- Protein: 33 g
- Cholesterol: 145 mg
Dietary
The photos in this post were taken by Megan McKeehan.
For ultimate success, we highly recommend reading the tips in the full blog post above. All photos and content are copyright protected. Please do not use our photos without prior written permission. If you wish to republish a recipe, please rewrite the recipe in your own unique words. Link back to the source recipe here on The Real Food Dietitians. Thank you!

